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DECEMBER 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 12 and interview author David Cane, whose article describes the characterization of a biosynthetic gene cluster in a mold that infects grapes. They also speak with Ali Tavassoli about a peptide that disrupts a protein-protein interaction in which the HIV Gag protein is a partner.
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 Audio (mp3 file) |  iTunes | Volume 3, Issue 12 Table of Contents |
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NOVEMBER 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 11 and interview author Michael Marletta, whose lab has published a study on the chemistry of heme-containing proteins containing an H-NOX domain. They also speak with Mark Gurney about compounds that one day might lead to drugs for the motor neuron disease spinal muscular atrophy by inhibiting an unexpected target inside cells. Authors Margaret Stratton, Diane Mitrea, and Stuart Loh describe a new approach for designing biosensors using alternate frame folding .
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 Audio (mp3 file) | iTunes | Volume 3, Issue 11 Table of Contents |
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OCTOBER 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 10 and talk with author Lynne Regan about promising new compounds that can selectively kill cancer cells by targeting protein chaperones. Michael Ferguson describes exciting new molecules that can inhibit the biosynthesis of surface glycoproteins vital to the virulence of Trypanosoma brucei, the causative agent of African sleeping sickness. Review author Carol Lutz focuses on alternative polyadenylation of messenger RNAs, and provides insights into a host of studies on this newly appreciated form of gene regulation.
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Audio (mp3 file) | iTunes | Volume 3, Issue 10 Table of Contents |
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SEPTEMBER 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 9 and speak with author Penny J. Beuning about using single molecule force spectroscopy to explore the DNA binding properties of the alpha subunit of DNA polymerase III. They also talk with Issue 8 authors Hugh Rosen, who discusses the identification of agonists of the sphingosine 1-phosphate receptor, and James Williamson, whose research describes a new method for the total enzymatic synthesis of the purine nucleotides ATP and GTP.
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Audio (mp3 file) | iTunes | Volume 3, Issue 9 Table of Contents |
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AUGUST 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 8.
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Audio (mp3 file) | iTunes | Volume 3, Issue 8 Table of Contents |
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JULY 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 7. Author Merritt Maduke discusses her lab's creation of the most potent inhibitors of a certain class of anion-transport proteins ever discovered. Hang Yin talks about his Review on targeting transmembrane domains of membrane proteins, and Paul Hergenrother's lab presents a method for detecting protein-DNA interactions and their inhibitors that uses photonic crystal biosensors.
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Audio (mp3 file) | iTunes | Volume 3, Issue 7 Table of Contents |
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JUNE 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 6. Author Georgyi Los and colleagues present a tagging system using single genetic fusion, and Expert Josh Coon discusses his group's current work on developing and utilizing new tools in mass spectrometry.
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Audio (mp3 file) | iTunes | Volume 3, Issue 6 Table of Contents |
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MAY 2008 |
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 ACS Chemical Biology editors highlight papers from Volume 3, Issue 5. Authors Jim LaClair and George O’Doherty discuss their article on how environmental signals effect development in the model worm C. elegans. John Katzenellenbogen describes inhibitors of the Estrogen receptor alpha, and Ronen Marmorstein talks about his research on Phosphatidyl-Inositol-3-Kinase and why it's an important regulatory protein to target in cancer.
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Audio (mp3 file) | iTunes | Volume 3, Issue 5 Table of Contents |
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APRIL 2008 |
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 ACS Chemical Biology Editors highlight papers from Volume 3, Issue 4, and interview author Aseem Ansari about his lab's study on the behavior of Hox transcription factors.
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Audio (mp3 file) | iTunes | Volume 3, Issue 4 Table of Contents |
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MARCH 2008 |
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 ACS Chemical Biology editors highlight papers from Volume 3, Issue 3, and interview author Lynne Regan about her lab's findings on a new way to study protein interactions that could have broader applications in cancer biology.
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Audio (mp3 file) | iTunes | Volume 3, Issue 3 Table of Contents |
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FEBRUARY 2008 |
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 ACS Chemical Biology editors highlight papers from Volume 3, Issue 2, and interview author Dehua Pei, who describes a robust platform for the detection of small molecules involved in bacterial quorum sensing. ACS Chemical Biology Editor-in-Chief Laura L. Kiessling explains how stimuli that attract or repel are perceived, and how a repellent can be converted into an attractant.
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Audio (mp3 file) | iTunes | Volume 3, Issue 2 Table of Contents |
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JANUARY 2008 |
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 ACS Chemical Biology editors highlights papers from Volume 3, Issue 1, a special issue focused on synthetic biology. The issue features reviews from the labs of Jay Keasling, Dek Woolfson, Christine Chow, and Oliver Rackham. Additional commentaries discuss emerging technologies for the production of biofuels.
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Audio (mp3 file) | iTunes | Volume 3, Issue 1 Table of Contents |
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PODCAST ARCHIVES |
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HOW TO HEAR OUR PODCASTS |
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