The ChemBioGlossary is a repository for key terms used by chemical biologists. All of these terms are featured in Reviews in the journal and authors have supplied initial definitions for them. We work in a multidisciplinary field, where one term can mean many things. Add to these definitions to help develop a robust chemical biology dictionary.
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Activator ATF
Activity-based protein profiling
Adenosine triphosphate (ATP)
Affinity
AFM (Atomic force microscopy)
AFPs (Autofluorescent proteins)
Agonist
AGT-based protein labeling
Allosteric
Amidinotransferases
Amidotransferases
Aminoacyl-tRNA Synthetases (aaRS)
Animal disease model
Animal model
Antagonist
Antibodies
Assay or screen
ATF (Artificial transcription...
ATM
ATR
Autoantibodies
Automated synthesis...
Bifunctional
Bio-orthogonal
Botulinum neurotoxin (BoNT)
Botulism
Caenorhabditis elegans
Catalytic antioxidants
Carbohydrate-based vaccines
Carbonate radical
Carrier-protein-based protein...
cbl defects
Cell imaging
Chaperones
Chemical genetics
Chemoenzymatic
Cholinergic transmission
Chromatin
CID (Chemical Inducers of...
CID (Collision-induced...
Citrullination
Clostridium botulinum
Coactivator
Cobalamin
Codon
Coenzyme
COMPASS
Conotoxins
Covalent intermediate
Cyclization
Cystine framework
Deacylation
Deiminase
Demethyliminase
Disulfide bridge
DNA binding domain (DBD)
DNA-PK
Double strand DNA break
Drosophila melanogaster
Drug Hyrbrid
ECD and ETD (Electron capture...
Editing site
Efficacy
Electrospray ionization (ESI)
Epigenetic information
Evolution
FCS (Fluorescence Correlation Spectroscopy)
Fourier transform MS (FT-MS)
FIONA (Fluorescence imaging...
FlAsH
Fluorescence microscopy
Fluorescence spectroscopy
Fluorophore
Free Radical
FRET (Fluorescence resonance...
FRET
Full agonist
Ganglioside
Gatekeeper residue
Genetic code degeneracy
Genotype
Glycome
Glycoarrays
Glycoform
Glycotools
Gonadotropin-releasing hormone...
GPI anchored protein
G-protein-coupled receptors
G-quadruplex
High-content screening
High-throughput screening
Histone
Histone demethylases
Histone methylation
Histone methyltransferases
Homocysteine
Homolysis
Hyperhomocysteinemia
Inborn errors
Integration
Intracellular trafficking
Invertebrates
Ion channels
Ion mobility spectrometry (IMS)
Ion trap MS
Lectin
Magic bullet
MALDI (Matrix-assisted laser...
Methylmalonic aciduria
Misacylation
Mobile proton mechanism
Molecular motors
MS/MS spectrum
MS3 spectrum
Multivalent
Mutant receptors
Nalmefene
Native chemical ligation (NCL)
Nitric oxide
Nonhomologous end joining
Nucleosome
Null effects
Operational model
Optical tweezers
Orthosteric
Partial agonist
Peroxiredoxins
Peroxynitrous acid/perox...
PeT (Photoinduced electron...
Phage display
Pharmacological chaperones
Pharmacodynamics
Pharmacokinetics
Pharmacoperone
Phenotype
Phosphorylation
PIC<sub>50</sub>
P<em>K</em><sub>B</sub>
Point mutation
Postintegration repair
PROTAC
Protein folding
Protein kinase
Protein kinase substrate
Protein transduction domains
Pulse-chase labeling
Quadrupole MS
Rate of dissociation
ReAsH
Retrovirus
Ribosomes
Riboswitch
Ribozyme
S-Alkylthiouronium
SELDI (Surface-enhanced laser...
SET-domain
Single-molecule methods
Small molecule
Small-molecule microarray
SNARE protein
Sparsomycin
Stimulus-responding coupling
Superoxide (O2)
Superoxide dismutase
Synaptosome
TAD (Transcriptional activation..
Telomere
Time-of-flight MS (TOFMS)
Transcriptional activator
Transfer RNA (tRNA)
Translocation
Transposon
Ubiquitin-dependent proteolysis
Yeast three-hybrid