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ChemBio Glossary—Phage display: A method for the selection of recombinant binding proteins from combinatorial, DNA-encoded libraries. Read more
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Disrupting the receptor coactivator interactions. Article by Gunther et al. Published Online May 14, 2009
Gunther et al. target the coactivator binding groove of the androgen receptor as an alternative approach to treatment-resistant prostate cancer therapy. Read Article
Translation Initiation and Cancer Article by Ghosh et al. Published Online April 7, 2009
Aberrations in cap-dependent translation initiation can lead to many cancers. Ghosh et al. describe the first non-toxic small molecule able to inhibit a key process causing these cancers. Read Article
ACS Chemical Biology author Terry Kenakin presents the fundamentals of Pharmacokinetics and Pharmacodynamics as they apply to the chemical structure of drugs. There will be specific discussion of the role of medicinal chemistry in the drug discovery process; how chemical structure affects the absorption, distribution, metabolism and excretion (ADME properties) of drugs; and drug affinity and efficacy (Pharmacodynamics). Learn more
Better Biosynthesis Building Blocks July 27, 2009—C&EN News Article
First Liquid Protein July 27, 2009—C&EN News Article
Analyzing Protein Drugs July 20, 2009—C&EN News Article