Do chemical biologists approach scientific questions with a different mindset than other related scientists?
I think chemical biologists have a broader perspective on their
research and aren't affraid to try new techniques. I wouldn't say that
any one lab does all of the chemistry and biology involved in a single
project, but rather that the chemical biologist collaborates more than
the average chemist and hence is able to address bigger
questions. For example, Tarun Kapoor, Bruce F. McEwen, and Alexey
Khodjakov recently published a very nice study in Science (20 January
2006). These labs used many techniques to study chromosome
orientation during cell division. It's a very impressive story. It is
clear from this study that collaboration was key to getting this story.
One wonders how many years and resources went into it.
I think chemical biologists are more inclined to use any technology
available to address the questions they are interested in, as opposed
to being limited by the traditional experiments and skill sets of a
specific scientific area.
Chemical
Biology is distinct from chemistry, biology, and biochemistry, in one
way, as follows: While biology, genetics, and biochemistry seeks to
probe complex biological systems at the level of genetic output, and
the level of phenotypes, chemical biology uses synthetic tools at the
chemical level instead. It uses the tools of chemistry, and the
insights into chemical bond formation and degradation, to probe and
manipulate the complicated systems of biology. - PG Holder, Oakland, CA
Reagent Chemical
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